Acupuncture and Laser Acupuncture as Treatments for Emotional Distress in Infertile Women in Japan.

Objectives: Needle and laser acupuncture are often used to improve the success rate of assisted reproductive technology (ART). This study examined whether needle or laser acupuncture ameliorated the emotional distress experienced by infertile women undergoing in vitro fertilization and embryo transfer (IVF-ET) or intracytoplasmic sperm injection (ICSI). Materials and Methods: Fifty-one infertile women who were undergoing IVF-ET or ICSI received needle acupuncture (needle-acupuncture group; n = 32) or laser acupuncture treatment (laser-acupuncture group; n = 19). The emotional distress experienced by the infertile women was evaluated using 2 questionnaires-the Profile of Mood States (POMS) and the State-Trait Anxiety Inventory (STAI)-both before and after 3 months of treatment. Results: In the needle-acupuncture group, the POMS detected significant post-treatment reductions in tension/anxiety (P < 0.001), depression/dejection (P < 0.001), anger/hostility (P < 0.001), confusion (P < 0.05), and total mood disturbance (TMD; p < 0.001). However, the POMS scores for vigor/activity and fatigue were not altered significantly after the treatment. In the STAI, both State and Trait scores had significantly decreased after the acupuncture (P < 0.001 and P < 0.05, respectively). In the laser-acupuncture group, the POMS detected significantly lower tension/anxiety (P < 0.05) and vigor/activity (P < 0.05) scores after the treatment. However, the POMS did not detect significant changes in depression/dejection, anger/hostility, fatigue, confusion, or TMD after the treatment. Furthermore, neither the STAI-State nor the STAI-Trait score had significantly decreased after the laser acupuncture treatment. Conclusions: These results indicate that needle and laser acupuncture ameliorate the emotional distress experienced by women who are undergoing IVF-ET or ICSI.

[Investigation of Factors Related to Stockpiling of Oral Care Hygiene Materials in Normal Times: Internet Survey Analysis].

OBJECTIVES: The aim of this study was to clarify the current status of stockpiling of oral care hygiene materials in case of a disaster and to determine methods to support stockpiling during disaster preparation. METHODS: We conducted an Internet questionnaire survey on stockpiling and disaster prevention measures among 300 adults. For statistical analysis, the χ² test, Mann-Whitney U-test and Spearman rank test were employed. Logistic regression analysis was conducted to review factors related to stockpiling. RESULTS: Among the questions on stockpiling and disaster prevention (14 of 15 items), seven items on disaster prevention measures and two on disaster prevention experiences significantly differed. Analysis of disaster prevention knowledge revealed that disaster prevention measures and disaster experiences significantly differed in terms of the presence or absence of stockpiling, albeit a positive correlation was noted with stockpiling. Logistic regression analysis was conducted with stockpiling as a dependent variable. As a result, the items 'I am aware about the hazard map of the residential area', 'I am aware about the type of oral care hygiene materials prepared for emergency' and 'Devising the living environment such that large furnitures and cupboards do not collapse during disasters' were effective. CONCLUSIONS: Stockpiling at home is considered necessary for self-sufficiency during a disaster on the basis of the experiences in disaster management, disaster prevention knowledge and disaster prevention measures. Hence, stockpiling is a strong measure against disaster prevention along with provision of appropriate knowledge about the necessity of oral care in daily life. Disaster prevention education that empowers a population to prepare itself by implementing disaster prevention measures, such as improving the home environment, is considered effective. In addition, considering that relying on stockpiling at an individual level is ineffective, it is necessary to create mechanisms and systems that jointly manage disaster situations according to local circumstances.

Behavioural Changes among University Students Examined Using Physical Activity Monitor.

OBJECTIVES: We examined the relationship between a physical activity monitor, which measures physical activities and health behavioural factors, and behavioural changes in 70 first-year university students who consented to participate among 80 students (recovery rate, 87.5%). METHODS: We evaluated Pearson's correlation coefficients using the Mann-Whitney U-test for changes in health behavioural factors and self-efficacy and performed binomial logistic regression analysis with health behavioural factors and self-efficacy as dependent variables and life improvement effects as explanatory variables. RESULTS: The analysis revealed a positive correlation among five items of expectations of life improvement, health behavioural factors and self-efficacy. The score of "health behaviour and expectations of life improvement effects" was higher than those of health behavioural factors and self-efficacy. Binomial logistic regression analysis revealed that self-efficacy is related to health behavioural factors, health behaviour and expectations of life improvement effects. CONCLUSIONS: Using the physical activity monitor to confirm behavioural science theory, health behavioural factors, self-efficacy and health behaviour are found to be effective for young adults to motivate themselves to maintain healthy behaviours.

Considering the effects purchase food balance guide utilizing cable television has on the user.

OBJECTIVES: The aim of this study was to empirically investigate the needfulness of the Purchased Foodstuffs Balance Guide as designed for its users and also consider its influence on better dietary habits. METHODS: The participants included 89 students who attended City A's Senior Citizens' College, and the reality of their ICT and dietary habits were surveyed. Next, 27 cable television subscribers were asked to be monitors for testing the Guide. The study took place during a period of September 2013 to March 2014. RESULTS: The results indicated that, for the senior citizens, ICT use was centred on communication with their families and that their awareness or desire was a low in terms of the functions of information transmission, entertainment and receipt of services. Next, after using the Purchased Foodstuffs Balance Guide, its needfulness and its influence on better food habits were examined. As a result, the most frequent response by the participants was that they 'understood [their own] purchasing tendencies' (36.0%), followed by the three items: 'The Guide is useful for managing my nutrition', 'The Guide enabled me to know what foodstuffs are required to supplement my diet' and 'I became more careful about purchasing foodstuffs in a balanced way.' CONCLUSIONS: The study showed that 70% of the participants felt that the Purchased Foodstuffs Balance Guide was useful and make decisions when purchasing food using the Guide. This indicates the possibility that the Guide exerts a positive influence on users' awareness of nutritional balance, foodstuff purchasing choices and dietary habits.

Effect on blood pressure of daily lemon ingestion and walking.

Background. Recent studies suggest that the daily intake of lemon (Citrus limon) has a good effect on health, but this has not been confirmed in humans. In our previous studies, it was observed that people who are conscious of their health performed more lemon intake and exercise. An analysis that took this into account was required. Methodology. For 101 middle-aged women in an island area in Hiroshima, Japan, a record of lemon ingestion efforts and the number of steps walked was carried out for five months. The change rates (Δ%) of the physical measurements, blood test, blood pressure, and pulse wave measured value during the observation period were calculated, and correlations with lemon intake and the number of steps walked were considered. As a result, it was suggested that daily lemon intake and walking are effective for high blood pressure because both showed significant negative correlation to systolic blood pressure Δ%. Conclusions. As a result of multiple linear regression analysis, it was possible that lemon ingestion is involved more greatly with the blood citric acid concentration Δ% and the number of steps with blood pressure Δ%, and it was surmised that the number of steps and lemon ingestion are related to blood pressure improvement by different action mechanisms.

[Effect of variation of lemon intake and walking in daily life on various indicators of muscle mass and blood biochemistry in menopausal middle-aged and elderly women].

OBJECTIVES: We examined the factors considered to change body composition and blood biochemistry indicators in menopausal middle-aged and elderly women. These changes result from exercise by walking as part of their daily activities and lemon consumption by women who live on the small islands of the Seto Inland Sea, Japan's largest citrus fruit (lemon)-producing region. METHODS: Between September 2011 and March 2012, we recorded the daily lemon consumption and the number of steps taken by 101 middle-aged and elderly female lemon farmers. We also measured their body dimensions, body compositions, and blood pressure pulse wave velocity and conducted blood tests before and after the survey period. The results before and after the survey period were compared by the t-test and associations were determined on the basis of Pearson's correlation coefficient. Covariance structural analysis was carried out to determine causal associations. RESULTS: From the results of covariance structure analysis, lemon intake did not have a direct impact on each item examined. The third item, i.e., "the factors related to arteriosclerosis," was affected indirectly via citric acid and fatigue, and anticoagulation was shown. The fourth item, i.e., "the factors related to maintenance of muscle mass," which is affected by menopausal years and the change in walking speed, was shown to be associated with the second item, i.e., "the factors related to lipid metabolism." Menopausal years affected the first, third and fourth items. CONCLUSIONS: Lemon intake did not have a direct impact on each item. Lemon has been shown to indirectly affect the third item through citric acid. Walking affected the second item, the level of total cholesterol, such as HDL cholesterol, through the fourth item. The importance of providing services that lead to sustained physical activity and a well-balanced metabolism between lipids and carbohydrates has been shown.

[Challenges and development of a nutritional management service system home page that targets personal computer novices 65 years of age or older].

OBJECTIVES: We intended to develop contents for nutritional management for elderly people using the Internet, and to consider factors relatied to the promotion of Information and Communication Technology (ICT) use. METHODS: A questionnaire survey was carried out consisting of items on diet support conditions and promoting the use of ICT by the elderly. Then, we developed a nutritional management system using a home page on a trial basis, after which n we studied the need, operability and environmental support of this system. RESULTS: Regarding the state of ICT use more than one- half of the respondents were daily users of the Internet 62.4%, and mobile phones 65.2%. On the four items on diet, such as "buy the same food, forget to buy food", 22.7%responded that "forget to buy food", which was the highest, and interest in "lunch home delivery" showed a low percentage. Among the respondents 19.6% answer "yes" to the question that memory, "have trouble remembering where you put things" and 13.4% responded that they forget to take medicine". There was a positive correlation of what with five items on operability, "What is simple and easy to use is good" and the effectiveness of personal computers and mobile phones has been shown. In addition, 32.3% responded "When the operation is difficult, the use becomes inconvenient". CONCLUSIONS: It was suggested that by setting up an opportunity to experience the effectiveness and the satisfaction of using a system that addresses elderly people's concerns, we can modify attitudes and provide motivation, reducing the sense of weakness or irrelevance that can hinder the use of a nutritional management system. It was suggested that along with the sense of effectiveness of screen displays with color instructions and simple design that match the physical characteristics of the elderly, the sense of being able to operate the system afterwards will affect the need for ICT use and utilization rate.

[Examination of influence of adolescent lifestyle on oral hygiene].

OBJECTIVES: In the "biopsychosocial model" propounded by Engel, psychological, biological, and social factors are considered to be interrelated contributors to the causes of illnesses. In this study, we investigated the relationship of oral health in Japanese juveniles with psychological, biological, and social factors. METHODS: The subjects were 227 junior high school students who belonged to a relatively small junior high school in A city, Hiroshima prefecture, Japan. The investigation period was from October 2010 to May 2011. The status of oral health was determined from the results of the caries risk test and periodontal examinations performed using saliva samples. In addition, subjective oral symptoms were determined using questionnaires. Thereafter, the interrelationships among psychological, biological, and individual social (mainly status in the family) factors and preventive methods against oral diseases were discussed. RESULTS: A large number of students were identified to have a high caries risk, and 20% of the students with periodontitis were in need of medical treatment. Oral health status was not influenced equally by the biological, psychological, and social factors. The results suggest that individual social factors influence biological changes through a psychological factor interaction. CONCLUSIONS: The findings suggest that oral disease prevention in juveniles requires an active positive influence of individual social factors, that is, relationships with family members and other individuals, such as medical and educational professionals and individuals involved in juvenile oral health improvement programs.

Decreased resting energy expenditure in patients with Duchenne muscular dystrophy.

BACKGROUND: Skeletal muscle metabolism is a major determinant of resting energy expenditure (REE). Although the severe muscle loss that characterizes Duchenne muscular dystrophy (DMD) may alter REE, this has not been extensively investigated. METHODS: We studied REE in 77 patients with DMD ranging in age from 10 to 37 years using a portable indirect calorimeter, together with several clinical parameters (age, height, body weight (BW), body mass index (BMI), vital capacity (VC), creatine kinase, creatinine, albumin, cholinesterase, prealbumin), and assessed their influence on REE. In addition, in 12 patients maintaining a stable body weight, the ratio of energy intake to REE was calculated and defined as an alternative index for the physical activity level (aPAL). RESULTS: REE (kcal/day, mean±SD) in DMD patients was 1123 (10-11 years), 1186±188 (12-14 years), 1146±214 (15-17 years), 1006±136 (18-29 years) and 1023±97 (≥30 years), each of these values being significantly lower than the corresponding control (p<0.0001). VC (p<0.001) was the parameter most strongly associated with REE, followed by BMI (p<0.01) and BW (p<0.05). The calculated aPAL values were 1.61 (10-11 years), 1.19 (12-14 years), 1.16 (15-17 years), and 1.57 (18-29 years). CONCLUSION: The REE in DMD patients was significantly lower than the normal value in every age group, and strongly associated with VC. Both the low REE and PAL values during the early teens, resulting in a low energy requirement, might be related to the obesity that frequently occurs in this age group. In contrast, the high PAL value in the late stage of the disease, possibly due to the presence of respiratory failure, may lead to a high energy requirement, and thus become one of the risk factors for development of malnutrition.

Analysis of the factors that affect dental health behaviour and attendance at scheduled dental check-ups using the PRECEDE-PROCEED Model.

A questionnaire survey was administered to 317 parents who attended infant health check-ups in City B, Okayama Prefecture between October, 2008 and March, 2009. The questionnaire survey studied 7 factors based on the PRECEDE-PROCEED Model. We analysed factors that affected oral health behaviour and attendance at scheduled dental health check-ups. The survey containing 22 items concerning matters such as 'QOL' and 'health problems' was posted to parents and guardians in advance, and then collected on the day of the medical check-up. The collected data was analysed using the t-test and Pearson's correlation coefficient, following which we conducted a covariance structure analysis. The results showed that dental health behaviour was directly affected by reinforcing factors, and indirectly associated with enabling and predisposing factors influenced by reinforcing factors. It was also shown that predisposing factors and oral health behaviour were associated with attendance at scheduled oral health check-ups. The results indicated that strengthening oral health education by sharing knowledge that acts as predisposing factors and introducing adaptations of oral health behaviour that that fit individual lives will lead to improved attendance at scheduled dental health check-ups.

[A case of autosomal recessive hypomyelinating leukodystrophy without GJA12 mutation presenting a novel phenotype].

A 50-year-old woman, who had consanguineous parents, developed gait disturbance at age 3, and revealed nystagmus, cerebellar ataxia, peripheral neuropathy, and spastic tetraparesis. She admitted to our hospital at age 14, and the symptoms progressed very slowly. MRI of this case at age 45 showed a remarkable, diffuse hypomyelination of the cerebrum. Her older sister who already deceased at age 16 showed neurological symptoms similar to this case. The patient was found to have no proteolipid protein-1 gene duplications and deletions and base substitution. Her symptoms were considered to be different from those of typical HLD2, 3, 4 and 5. She carried no GJA12 mutations. These facts suggested that this disease is a novel, autosomal recessive hypomyelinating leukodystrophy.

Salivary chromogranin A: useful and quantitative biochemical marker of affective state in patients with amyotrophic lateral sclerosis.

OBJECTIVE: To evaluate the affective state biochemically and quantitatively in amyotrophic lateral sclerosis (ALS) patients using salivary chromogranin A (CgA) measurement. SUBJECTS AND METHODS: Twelve moderate and 12 terminal ALS patients defined using the ALS Health State Scale were studied. The correlation between salivary CgA levels and the 40-item ALS assessment questionnaire (ALSAQ-40) scores was investigated in 12 moderate ALS patients. Moreover, salivary CgA levels in 12 terminal ALS patients, in whom the emotional functioning score could not be assessed, were compared with those in 12 moderate ALS patients, 7 patients with tube-fed vascular dementia, and in 26 healthy volunteers. RESULTS: There were individual differences in salivary CgA levels in spite of similar severity of disease; however, mean salivary CgA levels in terminal ALS patients, in whom the emotional functioning score based on interview could not be assessed, was significantly higher (12.58+/-2.79 pmol/mL) than in patients with moderate ALS (6.36+/-1.62 pmol/mL, p<0.05), tube-fed vascular dementia (4.04+/-2.04 pmol/mL, p<0.01), and healthy volunteers (3.77+/-1.90 pmol/mL, p<0.01). Moreover, a statistically significant positive correlation was observed between salivary CgA levels and emotional functioning scores on ALSAQ-40 in moderate patients (r=0.892, p<0.01). CONCLUSION: Salivary CgA may be a useful and quantitative biochemical marker of the affective state, not only in moderate, but also in terminal ALS. Periodic salivary CgA measurements over the long term and/or in various situations could have therapeutic implications for the quality of life of these patients.